Figure 1

Pyridostigmine-Induced Status Epilepticus Rat Model Was Resistant to Increasing Doses of Ramipril: The Latter Triggered Epileptogenesis, Arrhythmia, and Cardiac Ischemia in a Dose-Dependent Manner

Sherine Abdelmissih*, Monica Gamal and Kerollos M Naeem

Published: 20 March, 2025 | Volume 9 - Issue 1 | Pages: 010-027

jnnd-aid1106-g011

Figure 1:

ECG of adult male Wistar albino rats (N = 63). a. HR (bpm). b. P amplitude (mV). c. P duration (seconds). d. PR interval (seconds). e. R amplitude (mV). f. S amplitude. Data are expressed as median and interquartile range. g. ST height (mV). Data are expressed as mean ± SD. h. T amplitude (mV). i. QRS interval (seconds). j. QT (mV). k. QTc (mV). l. JT (mV). m. JTc (mV). n. TpTe (seconds). o. RR interval (seconds). Data are expressed as median and interquartile range. DMSO: Dimethyl-sulfoxide; PISE: Pyridostigmine-induced Status Epilepticus; SVPA: Sodium Valproate; TpTe: T end-Tpeak; QTc: Heart rate-corrected QT interval; JTc: heart rate-corrected JT interval; HR: Heart Rate; bpm: Beat per minute. p ˂ 0.05 is considered statistically significant. * p ˂ 0.05, ** p ˂ 0.01, *** p ˂ 0.001, and **** p ˂ 0.0001.

Read Full Article HTML DOI: 10.29328/journal.jnnd.1001106 Cite this Article Read Full Article PDF

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