Figure 3

Regulation of Fear Behavior by Microcircuits within the Mouse Amygdala

Cheng Wei* and Wen Yao*

Published: 10 March, 2025 | Volume 9 - Issue 1 | Pages: 001-009

jnnd-aid1105-g003

Figure 3:

The BLA receives and integrates sensory inputs from the thalamus and cortical regions, subsequently projecting to the lateral division of the central amygdala (CeL) to modulate fear expression levels. During fear learning, auditory stimuli enhance the activity of parvalbumin-positive (PV) neurons while suppressing somatostatin-expressing (SST) neurons. Both PV and SST neurons regulate fear output by inhibiting dendritic excitatory neurotransmission in the BLA during conditioned stimulus (CS) presentation, thereby controlling BLA-to-CeL projections and fine-tuning fear expression.

Read Full Article HTML DOI: 10.29328/journal.jnnd.1001105 Cite this Article Read Full Article PDF

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